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Nemoto Science

(주) Nemoto Science는 신약 개발 제네릭 의약품 개발에있어서의
약물 동태 시험 및 제제 시험 수탁 시험을 실시하고 있습니다

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Nemoto Science는 Takeda pharmaceutical과의 비임상서비스를 주로 제공하였기 때문에 신뢰할 수 있는 비임상 수탁 기관입니다.



STUDY MENU

In vivo DMPK studies

  • Absorption, Distribution, Metabolism, Excertion, studies with unapparelled levels of techniques
  • QWBA(Labelled compounds, Labeled cell)
  • Absorption route(Portal vein, Lymphatics)
  • Mass Balance(Excertion into the expires breath)
  • Metabolite structure estimation
  • In vitro DMPK studies

  • wide range of Studies using Radiolabeled/Non-labeled compounds
  • Metabolic stability, Metabolite profiling using cellular fraction or hepatocytes
  • Metabolite structure estimation
  • Plasma protein binding, Blood cell partitioning
  • Metabolic enzyme identification
  • CYP inhibition, CYP induction
  • Colalent binding
  • Caco-2 cellular permeability
  • Transporter assay
  • Custom synthesis and purification

  • Radiolabeled compound
  • Stable isotopes labeled compound
  • Metabolite
  • Bioanalysis

  • (Method development, Validation, Quantitative analysis of drug concentration)
  • Phamacokinetics(PK) study
  • Toxicokinetic(TK) study
  • Phase I~IV study
  • Bioequivalence(BE)study